國立臺灣大學醫學院分子醫學研究所

本所徐立中老師團隊論文成果發表《Nature Communications》
【臺大校訊第1313期】報導本所徐立中老師的研究團隊日前發表創新論文，首度揭開ZNRF1泛素連接酶(Ubiquitin ligase)透過細胞中小窩蛋白-1(caveolin-1)調控第四型類鐸受器(TLR4)所引發的發炎反應，此新發現對研發發炎相關疾病的治療 more »
6/16（五）Dr. Feng Ching Tsai專題演講，敬請踴躍參加
106學年度博士班招生口試名單
臺大分子醫學研究所李芳仁老師誠徵博士後研究員
106 學年度碩士班招生口試名單

Hsu J.-W., Tang P.-H., Wang I-H., Liu C.-L., Chen W.-H., Tsai P.-C., Chen K.-Y., Chen K.-J., Yu C.-J., and *Lee F.-J. S. (2016) "Unfolded protein response regulates yeast Arl1p activation at late-Golgi via phosphorylation of Arf GEF Syt1p" Proc. Natl. Acad. Sci. U S A. 2016 Mar 22;113(12):E1683-90. – 李芳仁老師
Tien SC, Lee HH, and Chang ZF. (2016) The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nature Comm. 7:10420 - 張智芬老師
Lee CY, Lai TY, Tsai MK, Chang YC, Ho YH, Yu IS, Yeh TW, Chou CC, Lin YS, Lawrence T, and Hsu LC* (2017) The Ubiquitin Ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation. Nat Commun. (In press) - 徐立中老師
Chen YC, Chen HJ, Tseng WC, Hsu JM, Huang TT, Chen CH, Pan CL. A C. elegans Thermosensory Circuit Regulates Longevity through crh-1/CREB-Dependent flp-6 Neuropeptide Signaling. Dev Cell 2016, 39: 1-15. – 潘俊良老師
Lin T., Pan PY., Lai YT., Chiang KW., Hsieh HL., Wu YP., Ke JM., Tang CY., Yang SB., Cheng HC., Wu JT., Jan YN. and Lee, HH. (2015) Spindle-F is the central mediator of Ik2 kinase-dependent dendrite pruning in Drosophila sensory neurons. PLoS Genetics 11(11): e1005642.– 李秀香老師
Chin, Y.H.*, Lee, A.*, Kan, H.W., Laiman J., Chuang, M.C., Hsieh, S.T. and Liu, Y.W. (2015), Dynamin-2 mutations associated with centronuclear myopathy are hypermorphic and lead to T-tubule fragmentation. Hum Mol Genet 24, 5542-54 (* equal contribution).– 劉雅雯老師
Tsai, H.Y., Chen, C.C., Conte, D. Jr, Moresco, J.J., Chaves, D.A., Mitani, S., Yates, J.R. 3rd, Tsai, M.D., and Mello, C.C. (2015) A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi. Cell. 29;160(3):407-19. - 蔡欣祐老師